Document Details
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Document Type |
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Article In Journal |
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Document Title |
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The genetic structure of native Americans in North America based on the Globalfiler® STRs The genetic structure of native Americans in North America based on the Globalfiler® STRs |
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Document Language |
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English |
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Abstract |
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Current forensic STR databases, such as CODIS, lack population genetic data on Native American populations.
Information from a geographically diverse array of tribes is necessary to provide improved statistical
estimates of the strength of associations with DNA evidence. The Globalfiler STR markers were used
to characterize the genetic structure of ten tribal populations from seven geographic regions in North
America, including those not presently represented in forensic databases. Samples from the Arctic region,
Baja California, California/Great Basin, the Southeast, Mexico, the Midwest, and the Southwest were analyzed
for allele frequencies, observed and expected heterozygosities, and F-statistics. The tribal samples
exhibited an FST or h value above the conservative 0.03 estimate recommended by the National Research
Council (NRC) for calculating random match probabilities among Native Americans. The greater differentiation
among tribal populations computed here (h = 0.04) warrants the inclusion of additional regional
Native American samples into STR databases. |
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ISSN |
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1344-6223 |
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Journal Name |
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Legal Medicine |
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Volume |
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23 |
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Issue Number |
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1 |
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Publishing Year |
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1437 AH
2016 AD |
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Article Type |
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Article |
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Added Date |
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Tuesday, July 18, 2017 |
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Researchers
| Kelly L. McCulloh | McCulloh, Kelly L. | Researcher | Doctorate | |
| Jillian Ng | Ng, Jillian | Researcher | Doctorate | |
| Robert F. Oldt | Oldt, Robert F. | Researcher | Doctorate | |
| Jessica A. Weise | Weise, Jessica A. | Researcher | Doctorate | |
| Joy Viray | Viray, Joy | Researcher | Doctorate | |
| Bruce Budowle | Budowle, Bruce | Researcher | Doctorate | |
| David Glenn Smith | Smith, David Glenn | Researcher | Doctorate | |
| Sreetharan Kanthaswamy | Kanthaswamy, Sreetharan | Researcher | Doctorate | |
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